Electric Swarm - Isaac runs to fall asleep to
36:05
Electric Swarm - Isaac runs to fall asleep to
231 views1 month ago
YouTubePadoody
All Custom Challenges - The Binding of Isaac: WhyBirth (Mod)
10:00
All Custom Challenges - The Binding of Isaac: WhyBirth (Mod)
233.9K viewsFeb 24, 2021
YouTubeSlayXc2
The Binding of Isaac: Afterbirth+ - How To Spawn Any Item
3:48
The Binding of Isaac: Afterbirth+ - How To Spawn Any Item
100.3K viewsJan 12, 2017
YouTubeLuke Vickery
THE BEST ISAAC MODS OF ALL TIME | The Binding of Isaac Afterbirth Plus
14:08
THE BEST ISAAC MODS OF ALL TIME | The Binding of Isaac Afterbirth Plus
253.3K viewsJun 19, 2020
YouTubeTearofGrace
001- Ultra Simple Modding (No Lua) | The Modding of Isaac Afterbirth+ with Lyte
18:14
001- Ultra Simple Modding (No Lua) | The Modding of Isaac Afterbirth+ with Lyte
183K viewsJan 4, 2017
YouTubeLytebringr
Lets investigate the balance patch
Lets investigate the balance patch
6K views2 months ago
Twitch
ALL ITEMS, 1 RUN
22:25
ALL ITEMS, 1 RUN
613.1K viewsSep 23, 2022
YouTubelavencas
0:42
This NEW Isaac Item Shreds EVERYTHING!
29.7K views5 months ago
YouTubeRomeLIVE
0:39
Godhead Just Got An INSANE Upgrade!
22.1K views5 months ago
YouTubeRomeLIVE
1:08
This NEW Isaac Item Changes EVERYTHING
22.2K views8 months ago
YouTubeRomeLIVE
0:14
Golden Purple Heart Upgrade!
30.2K views8 months ago
YouTubeBambochutafreak
11:50
Repentance CHAMPION Bosses! [Part 2/2] (Mod)
79.1K viewsApr 12, 2022
YouTubeSlayXc2
4:35
Isaac's Heart - Protect it
78.9K viewsJul 3, 2021
YouTubeSyncer
0:48
This NEW Isaac Mod Buffs EVERY RUNE!!
19.2K views8 months ago
YouTubeRomeLIVE
0:34
This NEW Mod Gives Isaac A CHAINSAW!
30.1K views5 months ago
YouTubeRomeLIVE
0:58
This BRAND NEW Isaac Item Buffs EVERYTHING!
141.3K views7 months ago
YouTubeRomeLIVE
8:39
All NEW BIRTHRIGHTS!!! (Isaac Repentance Patch)
250.9K viewsNov 11, 2021
YouTubeSlayXc2
0:45
This New Isaac Item Rewards Your SKILL
35.4K views8 months ago
YouTubeRomeLIVE
3:01
How does damage actually work?
3.4K viewsJun 21, 2024
YouTubeJack Smith
1:17:02
WELCOME TO REPENTANCE - The Binding Of Isaac: Repentance #1
630.1K viewsMar 31, 2021
YouTubeSinvicta
2:19
The New Isaac Patch – Worth Noticing?
781 viewsMar 10, 2025
YouTubeD0ggy
2:00
IPECAC + Trisagion got FIXED! (Isaac Repentance Patch)
263.1K viewsNov 11, 2021
YouTubeSlayXc2
0:57
Everything YOU Need To Know About The NEW Isaac Patch!
2.2K views8 months ago
YouTubeRomeLIVE
4:21
All Item Quality Changes In REPENTANCE+ (New Isaac DLC)
183.4K viewsNov 19, 2024
YouTubeSlayXc2
47:49
50+ Things You NEED TO KNOW from this Isaac Patch
104.2K views8 months ago
YouTubeAnother Matt Playing Isaac
0:28
This Modded Isaac Item Is ACTUALLY Broken 💀
15.6K views7 months ago
YouTubeRomeLIVE
29:07
Reviewing The NEW Binding of Isaac Patch Notes!
1.2K views8 months ago
YouTubeHoboDino
5:00
NEW Synergy in Patch 1.7.8! Brimstone + Soy Milk + Anti-Gravity
143.3K viewsMar 23, 2022
YouTubeSlayXc2
12:31
NEW AWESOME REWORKED BOSSES IN The Binding of Isaac: Repentance |Mod Showcase| Part 1
83.9K viewsJul 4, 2024
YouTubeYuri_Got_Coin
3:41
Tech.5 Got A Stealth Buff In Repentance+ !!! (It's Whacky)
74.1K viewsJan 10, 2025
YouTubeSlayXc2
See more
Static thumbnail place holder