HIV/AIDS is a priority for NIAID. Our research aims to: prevent new transmissions; end HIV-related deaths and complications; and discover a cure.

Learn more about HIV treatment as prevention. After I begin HIV treatment, how long does it take for the risk of sexually transmitting HIV to become effectively zero? There is effectively no risk of sexual …

Apr 11, 2024 · Herpes, caused by herpes simplex virus (HSV), has two subtypes—HSV-1 and HSV-2. HSV can be transmitted through sexual contact. In severe cases HSV may lead to life-threatening or …

Jan 3, 2025 · Malaria is a mosquito-borne infectious disease caused by the bite of female Anopheles mosquitoes, which spread infectious Plasmodium parasites into a host. Traditional malaria symptoms …

Severe combined immunodeficiency (SCID) is a group of rare disorders caused by mutations in different genes involved in the development and function of infection-fighting immune cells. Infants with SCID …

Prion diseases are transmissible, untreatable, and fatal brain diseases of mammals. Their cause is highly unusual: The host’s normal prion protein can, for unknown reasons, malfunction and assemble …

Figure 1. The mission of the NIH Strategic Plan for Herpes Simplex Virus Research is to improve diagnostic tools, prevention strategies, and treatments to reduce the public health impact of HSV. …

Dec 18, 2024 · A NIAID-sponsored analysis found that people with advanced HIV and anti-CD4 autoantibodies experienced limited CD4+ T-cell reconstitution through up to four years of observation …

Jan 6, 2025 · As health care services begin offering doxycycline to prevent bacterial sexually transmitted infections (STIs), real-world evidence demonstrates that the postexposure strategy, called doxy PEP, …

May 20, 2024 · An HIV vaccine candidate elicited trace levels of HIV broadly neutralizing antibodies and high levels of other key immune cells in an early-stage clinical trial. This immune response is an …