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  1. Coronavirus biology and replication: implications for SARS-CoV-2

    Oct 28, 2020 · In this Review, we summarize the first discoveries that shape our current understanding of SARS-CoV-2 infection throughout the intracellular viral life cycle and relate that to our...

  2. The Coronavirus Replication Cycle Explained - Biology Insights

    Jul 27, 2025 · These enveloped viruses, including SARS-CoV-2 (which causes COVID-19), are obligate intracellular parasites. They cannot multiply on their own; instead, they must invade and take over …

  3. SARS-CoV-2—Virus structure and life cycle - ScienceDirect

    By unraveling the intricate details of its genetic material, protein composition, and replication process, we have gained crucial insights into how SARS-CoV-2 infects and spreads within the human body.

  4. SARS-CoV-2 Life Cycle: Stages and Inhibition Targets

    The replication cycle of SARS-CoV-2 explained based on current literature. We provide a graphical representation of the SARS-CoV-2 Life Cycle with its St...

  5. A portrait of the infected cell: how SARS-CoV-2 infection reshapes ...

    SARS-CoV-2 manipulates host lipid metabolism by changing lipid composition to fuel viral replication and the formation of new virions. Ceramides and phosphatidic acids are upregulated to promote viral …

  6. The Life Cycle of SARS-CoV-2 - cwoer.ccbcmd.edu

    Early in the SARS-CoV-2 replication cycle, interactions between various nsps and host cell factors also initiate the formation of double-membrane replication organelles derived from the endoplasmic …

  7. SARS-CoV-2 Replication Revisited: Molecular Insights and Current …

    SARS-CoV-2 replication cycle and key molecular events targeted by antivirals. The SARS-CoV-2 replication cycle starts with (1) binding and viral entry, in which the virus attaches to the host cell …

  8. COVID-19: Coronavirus replication, pathogenesis, and therapeutic ...

    May 12, 2020 · The apparently large percentage of infections that are asymptomatic is unique to SARS-CoV-2, but many of the pathogenic features resemble those observed in SARS and MERS-CoV …

  9. COVID-19: from the structure and replication cycle of SARS-CoV-2 to …

    Apr 1, 2021 · This review focuses on basal characteristics of the SARS-CoV-2 virus - its structure, replication cycle, variants and course of infection. It also briefly characterizes the currently …

  10. Coronavirus Replication Mechanisms in Host Cells

    Apr 29, 2025 · The mechanisms of coronavirus replication within host cells are a key area of study, especially given the global impacts of viruses like SARS-CoV-2. Understanding these processes is …