Dec 9, 2024 · Adstiladrin (nadofaragene firadenovec-vncg) is a gene therapy used to treat high-risk Bacillus CalmetteGuérin (BCG)-unresponsive non-muscle invasive bladder cancer. …

ADSTILADRIN is a non-replicating adenoviral vector-based gene therapy indicated for the treatment of adult patients with high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non …

2 days ago · An example of this treatment advancement is nadofaragene firadenovec-vncg (Adstiladrin),a novel intravesical gene therapy for adults with BCG-unresponsive NMIBC with …

Clinical overview Indication: ADSTILADRIN® (nadofaragene firadenovec-vncg) is a non-replicating adenoviral vector-based gene therapy indicated for the treatment of adult patients …

Adstiladrin is also called nadofaragene firadenovec-vncg. Adstiladrin is a gene therapy that uses a non-replicating adenoviral vector (a modified virus that cannot multiply) to deliver a gene to …

Nadofaragene firadenovec uses a recombinant adenovirus that encodes for interferon alpha-2b gene. Intravesical instillation of interferon alone for bladder cancer produced complete …

Apr 1, 2025 · Abstract On December 16, 2022, the FDA approved the adenoviral vector-based gene therapy nadofaragene firadenovec-vncg (brand name Adstiladrin) for the treatment of …

Nov 12, 2025 · Simple Summary Some bladder cancers do not respond to the usual Bacillus Calmette-Guérin (BCG) treatment, leaving patients with few options, often requiring complete …

Feb 4, 2025 · Highlighting the Breakthrough ADSTILADRIN® (nadofaragene firadenovec) is the first FDA-approved gene therapy for a urological cancer, offering new hope for NMIBC …

Adstiladrin (nadofaragene firadenovec-vncg) is an FDA-approved gene therapy designed for high-risk BCG-unresponsive NMIBC. It represents a groundbreaking advancement in the treatment …