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  1. Osteoporosis - Symptoms and causes - Mayo Clinic

    Dec 17, 2025 · Symptoms There often are no symptoms in the early stages of bone loss. But once osteoporosis weakens your bones, you might have symptoms of a fracture that include: Back pain …

  2. Osteoarthritis - Symptoms & causes - Mayo Clinic

    Apr 8, 2025 · Osteoarthritis symptoms can usually be managed, although the damage to joints can't be reversed. Staying active, maintaining a healthy weight and receiving certain treatments might slow …

  3. Osteomyelitis - Symptoms and causes - Mayo Clinic

    Dec 10, 2024 · Overview Osteomyelitis is an infection in a bone. It can affect one or more parts of a bone. Infections can reach a bone through the bloodstream or from nearby infected tissue. Infections …

  4. Joint pain Causes - Mayo Clinic

    Apr 5, 2023 · Pain in a joint can be a symptom of many illnesses. Most often it's caused by some type of arthritis.

  5. Hypercalcemia - Symptoms and causes - Mayo Clinic

    Mar 8, 2024 · Hypercalcemia can cause stomach upset or pain, vomiting, and constipation. Bones and muscles. Most often, the extra calcium in the blood is leached from the bones. This weakens the …

  6. Arthritis - Symptoms and causes - Mayo Clinic

    Aug 29, 2023 · Arthritis is the swelling and tenderness of one or more joints. The main symptoms of arthritis are joint pain and stiffness, which typically worsen with age. The most common types of …

  7. Bone metastasis - Symptoms & causes - Mayo Clinic

    Jun 11, 2025 · Bone metastasis may be the first sign that you have cancer. Or bone metastasis may happen years after cancer treatment. Bone metastasis can cause pain and bones that break easily. …

  8. Multiple myeloma - Symptoms and causes - Mayo Clinic

    Dec 20, 2024 · Bone problems. Multiple myeloma can cause bone pain, thinning bones and broken bones. Kidney problems. Multiple myeloma may cause problems with the kidneys. It can lead to …

  9. Bone cancer - Symptoms and causes - Mayo Clinic

    Dec 5, 2024 · Symptoms Signs and symptoms of bone cancer include: Bone pain. Swelling and tenderness near the affected area. Weakened bone, which can lead to a broken bone. Feeling very …

  10. Tailbone pain: How can I relieve it? - Mayo Clinic

    Apr 21, 2023 · What causes tailbone pain, and how can I ease it? Tailbone pain is pain in or around the bony structure at the bottom of the spine. This part of the spine is called the coccyx. Tailbone pain is …