When the Rams take on the 49ers on Thursday night, the veteran quarterback will try to set a personal milestone with another ...

San Francisco 49ers running back Christian McCaffrey was the near-consensus No. 1 pick in fantasy football drafts. However, ...

McCaffrey's old backfield mate discussed the trials and tribulations of a season-ending injury on his podcast.

San Francisco 49ers head coach Kyle Shanahan addressed reporters during a Monday conference call, a day after the team's dominant 38-13 victory over the Chicago Bears. He shared several injury updates ...

With Christian McCaffrey and Jordan Mason on injured reserve, Guerendo made his first NFL start against the Bears. If he ...

Breaking down all of the good and some of the bad from the 49ers’ much-needed blowout win over the Bears in Week 14.

Kyle Shanahan confirmed his future is firmly with the San Francisco 49ers as far as he's concerned after leading them to a 38-13 victory over the Cleveland Browns to rescue their p ...

With both McCaffrey and Jordan Mason on injured reserve as the 49ers head down the stretch, they turned to rookie Isaac ...

Already missing five starters during the blowout loss to the Bills, San Francisco lost star running back Christian McCaffrey ...

SportsLine's model simulated Chicago Bears vs. San Francisco 49ers 10,000 times and made its Week 14 NFL picks, predictions ...

It's the final week of byes and also the swan song for the regular season in some fantasy leagues, making for an intriguing ...

San Francisco’s star running back McCaffrey is sitting on injured reserve once again, with the postseason getting ever nearer ...