Including the playoff game, Shanahan’s 49ers have beaten McVay’s Rams in 10 of 16 games. The two worked together for a year ...

San Francisco 49ers running back Christian McCaffrey suffered a knee injury and limped to the locker room in the second ...

San Francisco 49ers running back Christian McCaffrey has spoken out after being placed on injured reserve with yet another ...

Christian McCaffrey's injury-ridden season took another unfortunate turn when the star running back went down with another ...

Running back Christian McCaffrey is on injured reserve for the second time this season, but San Francisco 49ers coach Kyle ...

Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

The San Francisco 49ers on Wednesday continued adjusting to life without running backs Christian McCaffrey and Jordan Mason.

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

McCaffrey suffered a PCL injury during Sunday's loss to the Bills, while Mason went on IR with a high ankle sprain.

San Francisco 49ers star running back Christian McCaffrey will not need surgery on his injured right knee but will miss the ...

The 49ers lost running back Christian McCaffrey for the season with a knee injury. His backup, Jordan Mason, will also be ...

San Francisco 49ers running back Christian McCaffrey suffered an an apparent non-contact lower leg injury on Sunday Night ...