To quote the late, great Yogi Berra, ‘When you come to a fork in the road, take it,’” she told reporters at a press conference in Miami.

The aspirations of Florida’s first lady Casey DeSantis have long been a topic of discussion in Tallahassee. Her husband Gov.

Florida first lady Casey DeSantis, the wife of Gov. Ron DeSantis (R-FL), hinted at a gubernatorial run in 2026. Rep. Bryon Donalds (R-FL), whom President Donald Trump endorsed, already entered the race to be the Republican nominee in the state’s 2026 gubernatorial election.