Defensively, two of the 49ers’ best players this season are out and will not travel as defensive end Nick Bosa (obliques, ...

The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

The 49ers won't have their best pass rusher when they face the Bills on Sunday. Nick Bosa will miss his second game in a row with an oblique injury ...

Head coach Kyle Shanahan shared the final injury report on QB Brock Purdy, DL Nick Bosa and others and discussed the team's ...

First comes Brock Purdy, the team's star quarterback, who missed Week 12 with a right shoulder. While Purdy is still ...

San Francisco 49ers quarterback Brock Purdy appears to be making strides in his recovery from a shoulder injury. During the ...

San Francisco 49ers defensive end Nick Bosa (97) celebrates after sacking Tampa Bay Buccaneers quarterback Baker Mayfield ...

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

This week, Nick Bosa was asked about the 49ers' upcoming opponent, Bills quarterback Josh Allen. Here's what Bosa said. Q: ...

LB Fred Warner, WR Deebo Samuel Sr., RB Christian McCaffrey and DL Nick Bosa identified key areas for improvement as the team ...

Fred Warner has played through pain before. However, he made a stunning admission about one ailment he's playing with.

Bosa (hip/oblique) will not practice Wednesday, Nick Wagoner of ESPN.com reports. Bosa missed last Sunday's loss to the Packers after he was injured in the Week 11 loss to the Seahawks. Sam Okuayinonu ...