The San Francisco 49ers’ exceedingly deep backfield thinned out rapidly when running backs Christian McCaffrey and Jordan ...

San Fransisco 49ers running back Christian McCaffrey already missed the first eight games of the NFL season due to ...

San Francisco 49ers running back Christian McCaffrey broke his silence with a lengthy Instagram post after suffering a knee ...

Christian McCaffrey, at the premature end of a season that started late, too, waxed philosophical in a social media post on ...

Isaac Guerendo didn’t start in college until his final game.. He starts at running back for the 49ers Sunday against Chicago.

San Francisco 49ers running back Christian McCaffrey was placed on injured reserve for the second time this season after ...

Having suffered a knee injury that landed him on injured reserve during a snowy loss to the Bills on Sunday night, 49ers ...

San Francisco 49ers running back Christian McCaffrey suffered a knee injury and limped to the locker room in the second ...

Christian McCaffrey practiced little and played less this season, seeing action in four games with 65 touches. He is out for ...

McCaffrey immediately checked himself out of the game and ran right into the medical tent. The 49ers star RB missed the ...

McCaffrey went down with a PCL injury against the Buffalo Bills in Week 13 on Sunday. He was placed on injured reserve for ...

Christian McCaffrey suffered a PCL injury in the 49ers' Week 13 loss to the Bills. He addressed the injury on social media ...