Check out who's in and who's out for Week 13. Plus weather reports, last-minute free agency options, and Jake Ciely's fantasy ...

Sunday after the 49ers lost their seventh game, I asked Brock Purdy to make of the terrible season the 49ers are having. Here ...

The San Francisco 49ers are in dire straights after a blowout loss to the Buffalo Bills, and QB Brock Purdy knows it.

The 49ers take on the Bills on "Sunday Night Football" in Week 13. Here's the latest on if QB Brock Purdy will be available ...

Kirk Cousins threw four interceptions and tossed the Atlanta Falcons’ playoff plans into disarray. Brock Purdy couldn’t ...

San Francisco 49ers quarterback Brock Purdy feels sorry for the brutal injury suffered by Christian McCaffrey.

The situation for the San Francisco 49ers is so dire that Brock Purdy had to send a clear and forceful message to his ...

The 49ers decide whether or not to play quarterback Brock Purdy, dealing with injury, for Week 13 against the Bills on Sunday ...

San Francisco 49ers quarterback Brock Purdy official game status revealed for Week 13 primetime matchup against the Buffalo ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

The 49ers' other inactives are defensive linemen Nick Bosa (hip, oblique) and Jordan Elliott (concussion), cornerback ...

The San Francisco 49ers suffered another crushing defeat Sunday night, falling 35-10 to the Buffalo Bills. The loss marked ...