The San Francisco 49ers made 11 selections in the 2025 NFL Draft. Discover how each player is projected to fit into the team and what contributions they could make during the season.

Alfred Collins isn't your typical 49ers defensive tackle. Collins is built to defend the run. He's big and extremely difficult

After drafting Georgia edge rusher Mykel Williams in the first round, the San Francisco 49ers doubled down on rebuilding their defensive front by selecting Texas Longhorns defensive tackle Alfred Collins with the 43rd overall pick in the second round of the 2025 NFL Draft.