Acetyl-CoA synthetase-2 is an emerging key enzyme for cancer metabolism, which supplies acetyl-CoA for tumor cells by capturing acetate as a carbon source under stressed conditions. However, ...
Efficient Energy Extraction: The citric acid cycle is designed to efficiently extract energy from acetyl-CoA in the form of ...
The stage separating glycolysis and the citric acid cycle is the oxidative decarboxylation of pyruvate. This reaction ...
6-PPDQ, has emerged as an environmental concern due to its widespread detection and toxic effects. In a study published in Environmental Chemistry and Ecotoxicology, researchers from Southeast ...
In mouse models of Alzheimer's disease, the investigational drug candidates known as CMS121 and J147 improve memory and slow the degeneration of brain cells. Now, researchers have shown how these ...
The citric acid cycle is also known as the Krebs cycle or the tricarboxylic acid cycle. It is a series of reactions in a closed loop that are fundamental for cellular respiration. The citric acid ...
Chinese researchers have revealed a mechanism that triggers metastasis of hepatocellular carcinoma (HCC)—the most common type of primary liver cancer—through the production of acetate by ...
High-resolution cryo-electron microscopy makes it possible to study complex enzymatic processes in detail. With this method, a research team of the University of Potsdam and Humboldt-Universität ...
Growing up in Canada as a performer and musician, Joseph Moran paid little mind to science. Later in college, though, when he decided to study medicine, he found himself enjoying the challenge of his ...
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