Previous studies have shown increased sensitivity to warfarin immediately after heart valve replacement. [3,4,6] These studies were based on comparison of warfarin response between cardiac ...

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the Plasma Drug Concentration and the Prothrombin Response in 3 Normal Subjects and 1 Patient with Hereditary Resistance to Coumarin Anticoagulant Drugs after a Single Dose of Warfarin, 1.5 mg.

Starting dosage 0.25 mg once per week 3 mg once per day 1.5 mg once per day Maintenance dosage 0.5 to 2 mg once per week 7 to 14 mg once per day 4 to 9 mg once per day Given by self self self ...