This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).

The Kwanobuhle Initiation Task Team, made up of traditional leaders, health officials, police, religious leaders, and taxi industry players, visited hotspot areas.

Abstract: The accurate recognition of translational initiation sites (TISs) in genomic, cDNA and mRNA sequences is crucial to identifying the primary structure of the functional gene products - ...

The virusoid associated with rice yellow mottle virus encodes its own proteins; is it the exception that proves the rule, or the first of many more to come? It’s axiomatic in reviews of virusoids that ...

Translation initiation (TI) allows accurate selection of the initiation codon on a messenger RNA (mRNA) and defines the reading frame. In all domains of life, translation initiation generally occurs ...

Researchers have solved the the structure of the complex formed when mRNA is being scanned to find the starting point for translating RNA into a protein. The discovery provides a new understanding of ...

Translation is the process that makes a protein based on messenger RNA Researchers now have a 3D structure for the complex that scans mRNA to start making protein Understanding how translation begins ...

Genes must be expressed in precise levels and at the exact moment if the complex balance regulating cell activity is to be maintained. Messenger RNA (mRNA) conveys genetic information from DNA to ...

Over the past 15 years, sequencing of the human genome and The Cancer Genome Atlas (TCGA) project have led to comprehensive lists of single-nucleotide polymorphisms (SNPs) and gene mutations across a ...

Cap-independent translation is believed to play an important role in eukaryotic protein synthesis, but the mechanisms of ribosomal recruitment and translation initiation remain largely unknown.

DEAD-box RNA helicase Ded1 is thought to resolve secondary structures in mRNA 5'-untranslated regions (5'-UTRs) that impede 48S preinitiation complex (PIC) formation at the initiation codon. We ...