This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...
For decades, biology has relied on one central assumption: the genetic code is precise. DNA is transcribed into RNA, RNA is ...
A new study finds that at least one Archaea has surprisingly flexibility when interpreting genetic code, which goes against a ...
Researchers uncovered a microbe that treats one stop codon as both a termination signal and an amino-acid instruction, revealing surprising genetic flexibility that may inspire new ways to influence ...
Abstract: DNA is emerging as a promising medium for storing huge volumes of data in a confined space that remains intact for thousands of years. Although this technique is very efficient, especially ...
Liquid culture flasks of bacteria grown in yellow broth covered with tinfoil on a shaker. Bacterial strains needed to be tested every step of the way to create the highly compressed genome. Credit: ...
Peking University, June 27, 2025: To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University ...
Yale scientists have reprogrammed the genetic code of an organism, creating a novel genomically recoded organism (GRO) with only one stop codon, enabling the production of synthetic proteins with new ...