Background: Toll-Like Receptors (TLR) and Interleukin-1 Receptors (IL-1R) play a critical role in the innate immune response as microbial sensors, providing a bridge between the innate and adaptive ...
41 St. Joseph's Health Care London and University of Western Ontario, London, Ontario, Canada Objective The 1980 American College of Rheumatology (ACR) classification criteria for systemic sclerosis ...
Aims Treating to low disease activity is routine in rheumatoid arthritis, but no comparable goal has been defined for systemic lupus erythematosus (SLE). We sought to define and validate a Lupus Low ...
OBJECTIVE To determine the efficacy of the individual components of physiotherapy in subjects with anterior knee pain. METHODS An observer blind, prospective, factorial design randomised controlled ...
Objectives Interferon-γ (IFNγ) is the pivotal mediator in murine models of primary haemophagocytic lymphohistiocytosis (pHLH). Given the similarities between primary and secondary HLH (sec-HLH), ...
Objective: To further assess the construct validity of the three European Scleroderma Study Group (EScSG) preliminary activity indices for systemic sclerosis (SSc): for SSc as a whole, for diffuse SSc ...
1 Department of Neurology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands 2 Department of Neurology, University Medical Centre Utrecht, Utrecht, The Netherlands ...
Correspondence to Dr Murray Urowitz, Center for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, University of Toronto, Lupus Clinic, Toronto, ON M5T2S8, Canada; ...
1 Sydney School of Public Health, University of Sydney, Sydney, New South Wales, Australia 2 School of Public Health and Community Medicine, University of New South Wales, Sydney, New South Wales, ...
a Centre Hospitalier Universitaire Vaudois, Laboratoire de Rhumatologie, Lausanne, Switzerland , b Centre Medical Universitaire, Division d’Oncologie, Geneva, Switzerland Dr N Busso, Centre ...
Primary Care Sciences Research Centre, Keele University, Keele, Staffordshire, UK Correspondence to: G Peat Primary Care Sciences Research Centre, Keele University ...
Objectives (1) To develop risk prediction models for knee osteoarthritis (OA) and (2) to estimate the risk reduction that results from modification of potential risk factors. Method This was a 12-year ...
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