San Francisco 49ers running back Christian McCaffrey suffered a knee injury and limped to the locker room in the second ...

San Francisco 49ers running back Christian McCaffrey has spoken out after being placed on injured reserve with yet another ...

Christian McCaffrey's injury-ridden season took another unfortunate turn when the star running back went down with another ...

Running back Christian McCaffrey is on injured reserve for the second time this season, but San Francisco 49ers coach Kyle ...

Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

McCaffrey suffered a PCL injury during Sunday's loss to the Bills, while Mason went on IR with a high ankle sprain.

San Francisco 49ers star running back Christian McCaffrey will not need surgery on his injured right knee but will miss the ...

San Francisco 49ers running back Christian McCaffrey and top backup Jordan Mason are being placed on injured reserve.

San Francisco 49ers running back Christian McCaffrey suffered an an apparent non-contact lower leg injury on Sunday Night ...

The 49ers lost running back Christian McCaffrey for the season with a knee injury. His backup, Jordan Mason, will also be ...

The San Francisco 49ers placed running back Christian McCaffrey on injured reserve Tuesday a day after coach Kyle Shanahan ...