"It had the ring of something more important than just happenstance," he said of his reunion with Karen Lorre.

Kelsey Grammer, one of the highest-paid television actors of all time, is releasing a new book about his sister's tragic ...

Kelsey Grammer is opening up about the 1975 murder of his sister, Karen Grammer, in his new book "Karen: A Brother Remembers.

Kelsey Grammer says that he drank, used drugs, and engaged in 'fairly exotic sexual behavior' to cope with the horrific ...

Kelsey Grammer revealed how his sister Karen's murder shattered his faith in God, and he explores his journey through grief ...

What happened to Kelsey Grammer’s sister Karen? Learn how her tragic 1975 murder shaped his life and inspired his new memoir, ...

A Brother Remembers,' Kelsey Grammer details using alcohol and cocaine to cope with his sister's rape and murder in 1975 ...

Kelsey Grammer's sister Karen was tragically kidnapped, raped and stabbed to death. Here's everything to know about what ...

Kelsey Grammer detailed his sister Karen Grammer’s final moments before her tragic death, nearly 50 years after the ...

Kelsey Grammer detailed his sister Karen Grammer’s final moments before her tragic death, nearly 50 years after the ...

Grammer does not flinch on the horrific details surrounding Karen’s rape and murder, but they are only a small part of the ...

Kelsey Grammer has struggled with the loss of his sister, Karen Grammer, for decades. But now, the Cheers alum is opening up ...