University of Texas Southwestern Medical Center scientists found that activating fibroblast growth factor 21 (FGF21) ...

Background:In obesity and type 2 diabetes mellitus (T2D), adipose tissue expansion (because of larger adipocytes) results in reduced microvascular density which is thought to lead to adipocyte hypoxia ...

In the lean, healthy state, adipose tissue (AT) has critical roles in maintaining organismal homeostasis. Paramount among the various roles of AT is the regulation of whole body metabolism. While ...

In medically indicated weight loss, attention is typically focused on the associated health benefits. However, recent ...

Growing evidence suggests a critical role for overnutrition in the development of low-grade inflammation. Specifically, chronic inflammation in adipose tissue is considered a crucial risk factor for ...

New nanobody-based method, POD-nAb/FT-GO 3D-IHC, enables ultra-fast, high-resolution labeling of neurons and glia deep within 1-mm-thick brain tissue, revealing cellular structures in just three days.

Endocannabinoids modulate insulin and adipokine expression in adipocytes through cannabinoid receptors and their levels are elevated during hyperglycemia and obesity, but little is known about how ...