Chondrocytes play a crucial role in skeletal development. Many bones, such as those in the arms and legs, are formed through ...

We elucidated that DNA methyltransferase 1 (Dnmt1), an epigenetic regulator, properly controls bone elongation by modulating energy metabolism in growth plate chondrocytes. Epigenetic regulation is ...

Bone health and development in children and adolescents are key factors for lifelong skeletal strength. During adolescence, about half of an adult’s bone mineral content is accumulated, with over 80% ...

Researchers at Science Tokyo have uncovered two distinct stem cell lineages responsible for forming tooth roots and surrounding bone, revealing the signaling networks that orchestrate their ...

Research led by Vladimír Sládek sheds new light on how bones age, questioning long-standing assumptions that sedentary lifestyles are the primary cause of weakening bone strength in modern humans.

Centre for Pharmaceutical Nanotechnology, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar (Mohal), Punjab 160062, India ...