Antibodies show promise as candidates for therapeutics as well as tools for advancing mechanistic studies of the HER family receptors.

For some proteins, a single mutation, or change in its DNA instructions, is all it takes to tip the balance between functioning normally and causing cancer.

Scientists at NYU have created a drug that targets cancer-causing HER2 mutations without harming healthy cells. This new ...

A previvor is essentially someone who has a genetic predisposition to certain cancers, but who may or may not currently have ...

Researchers obtain detailed picture of the specific mechanisms by which each individual mutation studied impacts drug response.

The past decade has witnessed a rapid expansion of genetic tests, including new instruments to inform patients who have been ...

All cancer mutations that cause drug resistance fall into one of four categories. New research has detailed each type, helping to uncover targets for drug development and identify potential effective ...

There isn’t a single answer to what causes pancreatic cancer because it involves multiple factors. Here’s what science knows ...

In a potential advance for melanoma patients, researchers at ChristianaCare's Gene Editing Institute have used CRISPR gene ...

Breast cancer in men can be misdiagnosed or overlooked because it’s so rare, but early detection can be lifesaving.

Analysis - Breast cancer is the number one cancer among women: more than 2 million cases were diagnosed worldwide in 2022. It is also particularly challenging to treat. Physiologist Anna-Mart ...