Medindia

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eLife

Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with nuclear speckles

HIV hijacks SRRM2 to enlarge nuclear speckles, stabilizing CPSF6 puncta and promoting efficient viral replication.

Insight Molecular Diagnostics Inc.: iMDx Prepares for U.S. Commercial Launch of GraftAssureDx as Clinical Trial Nears Completion

GraftAssure technology adoption further broadens with 20 global transplant centers engaged by year-end 2025, including first Canadian siteGraftAssureDx FDA IVD approval application 95% complete at yea ...
eLife

Fragile nucleosomes are essential for RNA Polymerase II to transcribe in eukaryotes

Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...

iMDx Prepares for U.S. Commercial Launch of GraftAssureDx as Clinical Trial Nears Completion

GraftAssure™ technology adoption further broadens with 20 global transplant centers engaged by year-end 2025, including first Canadian ...