The understanding of the biology of CRPC and the evidence that CRPC still remains driven by androgen receptor signaling led to the discovery of new therapeutic targets. In the last few years ...
Dr. Ryuma Tanaka presented the results of a retrospective study of patients with metastatic hormone sensitive prostate cancer (mHSPC) and the impact of delayed administration of androgen receptor ...
The androgen receptor is often activated despite resistance to available androgen receptor signaling inhibitors, with androgen receptor splice variants being detectable, and androgen mutations being ...
The role of androgen signalling in avian sexual development is still unclear. This study generated androgen receptor knockout chickens and find that, despite developing typical gonads, the males ...
They have a high affinity for the progesterone receptor (PR) ( Table 1), a strong anti-gonadotrope activity, as well as an intermediate affinity for androgen receptors. First-generation OCs ...
Endothelin is a peptide hormone known for its vasoconstrictive effects. Researchers at University of Tsukuba used ...
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*Corresponding Author: Matthew C. Dallos, Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 300 East 66th Street, Room 1219, New York, NY 10065. E-mail: ...