In a recent study published by Nature Communications, researchers uncovered a previously unknown method by which androgen-activated androgen receptors (ARs) increase fucosyltransferase 4 (FUT4 ...

The combination of cabozantinib and atezolizumab appeared more effective than switching ARPI therapy in patients with mCRPC and extrapelvic soft-tissue metastases.

One of the other, very obvious changes was the breast cells that appear to show the highest level of estrogen receptor signaling were reduced dramatically in proportion to the androgen-treated breast.

Traditional therapies targeting androgen receptor (AR) signaling have limited efficacy. In a recent study, researchers investigated the potential of azolato-bridged dinuclear platinum ...

A protein called the androgen receptor normally functions to guide the development of the prostate—signaling the cells to stop growing, act as normal prostate cells and maintain a healthy state.

Their study (“A TBX2-Driven Signaling Switch from Androgen Receptor to Glucocorticoid Receptor Confers Therapeutic Resistance in Prostate Cancer”), which was published in December 2024 by ...

RedHill Biopharma Ltd. (NASDAQ: RDHL) ("RedHill" or the "Company"), a specialty biopharmaceutical company, today announced ...

In 2022, there were 2.3 million women diagnosed with breast cancer and 670,000 deaths worldwide, according to the World ...

A new single-cell endometrium atlas shows how PCOS alters endometrial cell composition, disrupts hormone signaling, and ...

The inhibition of androgen / androgen receptor signaling can be used for the treatment and preventiojn of diseases such as cancer, insulin resistance, dyslipidemia, hypertension, ...