LATS1/2-inactivation and consequent nuclear YAP/TAZ hyperactivation in the mammary epithelium drives the development of a pro ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

Although obese individuals are at greater risk of diabetes, high blood pressure or high cholesterol, not all obese people ...

We find that reducing SirT1 expression in lean animals is sufficient to cause adipose tissue NF-κB activation, tissue and plasma cytokine elevations, and macrophage infiltration similar to that ...

The mammalian white adipose tissue is now recognized as a source of endocrine and paracrine signaling molecules playing a crucial role in many physiological and metabolic functions. These ...

Biomedical scientists at the University of California, Riverside have received a $3.7 million grant from the National Institutes of Health to study the role of sex-specific immune responses in obesity ...