Objective: We sought to determine whether adipose tissue is inflamed in individuals with increased liver fat (LFAT) independently of obesity. Results: Expression levels of the macrophage marker ...

Diabetes. 2007;56(8):1960-1968. In conclusion, we demonstrated that adipose tissue is infiltrated with macrophages and that its content of long-chain triacylglycerols and ceramides is increased in ...

This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

Research has uncovered key differences in gene expression linked to inflammation, metabolism and cardioprotection. These findings could help inform the development of targeted therapies for ...

As many as 40% of Americans are obese, putting them at an increased risk for high blood pressure, diabetes, stroke, heart disease and certain cancers, according to the CDC.

Understanding why newborns, but not adults, can regenerate the heart could lead to treatments that "reprogram" adult ...

Newborns with heart complications can rely on their newly developed immune systems to regenerate cardiac tissues, but adults ...

An increase in high-fat, high-fructose foods in people's diets has contributed to a dramatic increase in type 2 diabetes.

This important study focused on characterizing clonally derived MSC populations from the synovium of normal and osteoarthritis (OA) patients, demonstrating their potential to regenerate cartilage in ...