EMBO Press4d
A bacterial network of T3SS effectors counteracts host pro-inflammatory responses and cell death to promote infection
Host cells activate cell death pathways in response to bacterial manipulation of innate immune signalling, but the molecular ...
EMBO Press4d
PARP7 as a new target for activating anti-tumor immunity in cancer
PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...
EMBO Press2d
Beyond mitotic arrest: the diverse effects of microtubule-targeting drugs on tumor vasculature
For decades microtubule-targeting agents (MTAs) have been a cornerstone of cancer treatment regimens and continue to be heavily employed as backbone chemotherapy in combination with new targeted ...
EMBO Press8d
A new hybrid post-translational modification—have you lost your (MARUb)les?
Recent work in The EMBO Journal describes a new hybrid post-translational modification of proteins, composed of a poly-ubiquitin chain that is attached to a target protein via a mono-ADP-ribose (MAR) ...
Opinion
EMBO Press10dOpinion
Under pressure
US research has been under political pressure for some time. Examples include regulatory overreach on federal stem-cell research informed more by religion than scientific arguments, a growing vaccine ...
EMBO Press10d
NIH’s 15% cap: a cost comparison and research outlook
Overnight, leading research institutions in the USA have potentially lost billions of dollars in indirect funding, in a move that will likely change the biomedical research landsc ...
The EMBO Journal2d
Selective tubulin-binding drugs induce pericyte phenotype switching and anti-cancer immunity
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The intratumoral immune milieu is crucial for ...
The EMBO Journal3d
Persistent epigenetic memory of SARS-CoV-2 mRNA vaccination in monocyte-derived macrophages
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Immune memory plays a critical role in the ...
The EMBO Journal3d
Modulating CCTG repeat expansion toxicity in DM2 Drosophila model through TDP1 inhibition
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Targeting Tyrosyl-DNA phosphodiesterase 1 ...
The EMBO Journal2d
Mitochondrial fatty acid oxidation regulates adult muscle stem cell function through modulating metabolic flux and protein acetylation
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The bioenergetic requirements of muscle stem ...
The EMBO Journal11d
Targeting FKBP51 prevents stress-induced preterm birth
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Maternal stress is a major risk factor for ...