Background Idiopathic pulmonary fibrosis (IPF) is a disease of progressive lung scarring. There is a known association ...

Background Bronchoalveolar lavage (BAL) is essential in determining the efficacy of novel therapies in alpha-1 antitrypsin deficiency (AATD). These require initial proof-of-concept demonstration that ...

Background The evidence base on montelukast-associated adverse outcomes is inconclusive in children and young persons (CYP) with asthma. We aimed to investigate 1-year incidence of neuropsychiatric ...

Environmental factors, here taken to include pollutants, lifestyle factors and behaviours, can play an important role in serious, chronic pathologies with large societal and economic costs, including ...

Introduction Chronic rhinosinusitis with nasal polyposis (CRSwNP) affects a significant proportion of people with severe asthma (SA). Despite the effectiveness of anti-IL5/5R therapies in the ...

8 Biometrics, Late-stage Development, Respiratory and Immunology, BioPharmaceuticals RandD, AstraZeneca, Cambridge, UK 9 Late-stage Development, Respiratory and ...

12 Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada Correspondence to Dr Wan C Tan, UBC James Hogg Research Centre, Providence Heart+Lung Institute, University of ...

Atypical radiological manifestation of sarcoidosis presenting with an anterior mediastinal mass ...

Introduction Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the technique of choice in the evaluation of malignant lymph nodes and staging of lung cancer. However, ...

Background Asthma remains the most common chronic disease in children and the UK has some of the poorest asthma outcomes in Europe. The socio demographic inequalities contribute to severe asthma ...

2 Institute of Respiratory Medicine, University of Sydney, NSW, Australia 3 South Western Sydney Clinical School, University of New South Wales, NSW, Australia Background: Sahaja Yoga is a traditional ...

Background Patient perception of asthma treatment is rarely captured, and no specific tools exist to measure it. We developed an inhouse severe asthma patient feedback questionnaire (SAPFQ) using ...