Nearly a year after alarms about CAR T-cell therapies possibly causing secondary lymphomas, studies suggest that genetic predisposition—not vector integration—are likely the primary cause of these ...

Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan. *Corresponding Author: Max S. Wicha, Department of Internal Medicine, University of Michigan–Ann Arbor, 2800 Plymouth Road ...

Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International ...

Major Finding: Transferrin receptor targeting chimeras (TransTAC) can degrade many membrane proteins of interest. Concept: Coupling membrane proteins to transferrin receptor 1 enables efficient ...

Department of Allergy, The First Affiliated Hospital of Anhui Medical University and Institute of Clinical Immunology, Anhui Medical University, Hefei, China.

College of Pharmacy, Vessel-Organ Interaction Research Center (VOICE, MRC), Kyungpook National University, Daegu, Republic of Korea.

mRNA vaccines for COVID-19 were associated with higher PD-L1 expression in tumors and improved overall survival in patients with non–small cell lung cancer and metastatic melanoma who also received ...

This article (1) has been retracted at the request of the editors. An internal review by the editors found that the same image was used to represent Total VEGFR-2 in lanes 1–6 and in lanes 7–12 in Fig ...

The Nobel Prize in Physics was awarded to John Hopfield, PhD, and Geoffrey Hinton, PhD, for their pioneering work in artificial neural networks, which laid the foundation for modern AI applications in ...

This article (1) has been retracted at the request of the editors. An internal review by the editors found that: The same image was used to represent the TSP1 Western blot in Fig. 4B for the No lysate ...

The 2024 Nobel Prize in Medicine or Physiology recognized the discovery of microRNAs, small noncoding RNAs vital to regulating tumor biology. While early enthusiasm for microRNA-based therapies has ...

Three scientists will share the Nobel Prize in Chemistry for creating computational tools that transformed protein structure prediction and design, accelerating cancer research and drug discovery.