In mammalian cells, the nucleolus is the central site for ribosome biogenesis. It is composed of distinct subcompartments: the fibrillar center (FC), the dense fibrillar component (DFC), the periphery ...

The objective of this study was to utilize sub-nucleolar fractionation to elucidate the role of PHF6 in regulating rDNA expression. We observed nucleolar PHF6 to be localized within both the FC and ...

This is a preview. Log in through your library . Abstract To understand how nuclear machineries are targeted to accurate locations during nuclear assembly, we investigated the pathway of the ribosomal ...

This is a preview. Log in through your library . Abstract The four nucleolar proteins NOP1, SSB1, GAR1, and NSR1 of Saccharomyces cerevisiae share a repetitive domain composed of repeat units rich in ...