The actor was diagnosed with multiple sclerosis in June 2021 and shared her illness publicly in August that year.

And since revealing her diagnosis, Applegate has been open in speaking out about some of the 'weird' symptoms she experienced - not realizing at the time they were a sign of MS. In an ABC News interview, Applegate told Robin Roberts that there was one particular symptom which began 'in the early part of 2021'.

Christina Applegate's revealed her multiple sclerosis (MS) diagnosis publicly in 2021. Here's everything she's said about the disease and her symptoms.

During the Wednesday, Dec. 11 episode of MeSsy, the podcast she co-hosts with Jamie-Lynn Sigler, Applegate, 53, recalled falling while filming a scene of her character running across a field.

Christina Applegate dismissed early multiple sclerosis (MS) symptoms while filming Netflix's Dead To Me. The actor starred as Jen Harding in the Emmy-nominated dark comedy, which premiered in 2019 and ran for three seasons.

Actress Christina Applegate has been open about her struggles with multiple sclerosis, which she was diagnosed with back in 2021 — but evidently, her symptoms had already been present two years prior.

Christina Applegate is getting candid on her Multiple Sclerosis diagnosis. Although the actress, 53, wasn’t officially diagnosed until 2021, she first noticed mysterious symptoms two years earlier while shooting the pilot for the Netflix series “Dead To Me.