In addition to being featured in Outlander: Blood of My Blood, McCardie was known for his roles in the films The Ghost and the Darkness (1996), Speed 2: Cruise Control (1997) and Rob Roy (1995) and the TV show Line of Duty. The actor also played Sir Marcus MacRannoch in the original Outlander.

The episode ends with a dedication card for the memory of Brian McCardie. McCardie, who died unexpectedly in April 2024, plays Isaac Grant on the series. Grant is the chieftain of his clan, and as such, he poses a threat to Colum (Seamus McLean Ross), Dougal ( Sam Retford ), Ellen ( Harriet Slater ), and all of the MacKenzies.

Blood of My Blood" Ellen continues prepping for her arranged marriage while thinking of her beloved Brian. Along the way, Ellen learns some concerning information about the Grants.