A vulnerability in liver tumor cells' nuclear gateways could pave the way for new treatments

A study led by the Cell Cycle and Cancer Group at the Vall d'Hebron Institute of Oncology (VHIO) has identified a ...

Cancer-linked gene uses 'shortcut' to trigger cell division

Living cells are one of the few materials that can replicate themselves, and this is crucial for tissue development and ...

The hidden role of a cell-cycle regulator in senescent cells that don't divide

In a tale of identities as divergent as "The Prince and the Pauper," a well-known cancer-causing gene also influences cells ...
BIOENGINEER

WEE1 kinase guards quiescent cells’ path back into the cell cycle

A Nature study shows that the WEE1 kinase promotes cell cycle re-entry from quiescence by phosphorylating CDH1 to inhibit the ...
Nature

An unexpected function of a cell-cycle enzyme might explain the toxic effects of its inhibitors

A previously unknown mechanism required for cells to start proliferating has been identified. A combination of mathematical modelling and cell-based experiments shows that the enzyme WEE1 switches off ...

Scientists Discover a Hidden Weakness in Cancer Cells That Could Transform Treatment

Cancer cells that have lost one safeguard against DNA damage can become dependent on another, an enzyme called Wee1. Drugs ...
Feedstuffs

Glowing biosensor tracks cell division in chickens

The system uses fluorescent proteins that make cells glow in different colors as they move through the different stages of the cell cycle. This allows researchers to observe cell division and growth ...