Breakthroughs, discoveries, and DIY tips sent six days a week. Terms of Service and Privacy Policy. A team of researchers has uncovered a new biological editing ...

A team of researchers led by Feng Zhang at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT has uncovered the first programmable RNA-guided system in ...

Researchers have used computational methods to predict what could be a prokaryotic RNA-silencing mechanism similar to the eukaryotic RNA- interference system. A study published today in the open ...

Both prokaryotes and eukaryotes respond to the same RNA structure, initiating protein synthesis and thereby defying longstanding expectations. Prokaryotes and eukaryotes, it was long believed, relied ...

Figure 1: Reconstitution of B. subtilis SRP–ribosome complexes. Figure 5: SRP S domain–ribosome interaction at the ribosome exit. Figure 6: SRP Alu-domain interaction with the ribosome. Together, the ...

Hardly anyone would run an RNA gel without a ladder, but transcriptomes are mostly sequenced without the use of external standards. The added layer of transcript isoform complexity in eukaryotes as ...

Enzymes have clearly defined active sites to allow the substrate molecule to fit intricately. This is often coupled with an enzymatic conformational change prior to the occurrence of the catalysis ...

This method for directly enriching the 5´ end of primary transcripts enables the determination of transcription start sites at single-base resolution. Coupled with long read sequencing, the method ...

The origin of eukaryotes is considered one of the greatest enigmas in biology: according to current doctrine, two prokaryotes, a so-called Asgard archaeon and a bacterium, are believed to have merged.