Increased plaque forming capability of N protein mutant viruses carrying either S202R or R203M mutations A recent paper by Syed et al. demonstrates that mutations in the Nucleocapsid (N) protein, one ...
In a recent study posted to bioRxiv*, researchers developed a screening platform and identified molecules with anti-coronavirus (anti-CoV) activity. Study: A screen for modulation of nucleocapsid ...
A cross-institutional effort between researchers at Weill Cornell Medicine and Duke University has yielded exciting progress in the search for new therapeutics against Covid-19. Where much of our ...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-sense, single-stranded (ss) RNA virus. Upon binding to the angiotensin-converting enzyme 2 (ACE2) receptor, the virus ...
Despite the unprecedented global response to SARS-CoV-2, which has generated over 250,000 publications in two years, critical aspects of SARS-CoV-2 biology, pathogenesis, and immunomodulation remain ...
Filoviruses—such as Ebola and Marburg viruses—can cause hemorrhagic fevers with up to 90% lethality. Not only that, but there are very few tools (vaccines or drugs) to combat them. Now, scientists at ...
In this Application Note, Sartorius discusses and comprehensively characterizes the interaction between the SARS-CoV-2 Nucleocapsid (N) protein (presented as the first secreted human coronavirus viral ...
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