Syndex Bio, a biotechnology company advancing next‑generation molecular diagnostics, today announced the introduction of its proprietary mcPCR ™ (methyl‑copying PCR) platform at the Advances in Genome ...

Non-Hodgkin’s Lymphoma After Primary Hodgkin’s Disease in the German Hodgkin’s Lymphoma Study Group: Incidence, Treatment, and Prognosis PURPOSE: To investigate the frequency of p15 and p16 gene ...

Regular screening practices can identify malignant disease at an early stage, which may provide promising therapeutic options for patients, resulting in improved long-term outcomes. However, for some ...

In this ‘Peek behind the paper’, Elena Martens-Uzunova (left), Assistant Professor in the Department of Urology at the Erasmus University Medical Center (Rotterdam, The Netherlands), discusses her ...

Immunohistochemical and gene expression profiles as predictors of survival in recurrent high-grade glioma treated with intracranial nivolumab, ipilimumab, and ...

Methylation analysis holds significant promise for clinical diagnostics, yet its use has been limited due to challenges posed by legacy technologies that undermine clinical applicability, such as ...

Recently, BGI Genomics' COLOTECT™ 1.0 DNA Methylation Detection Kit for Human SDC2, ADHFE1, and PPP2R5C Genes (Real-Time PCR), Sample Pretreatment Kit for Methylation Detection, DNA Isolation Kit, ...

The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.

DNA methylation is a fundamental epigenetic mechanism in which a methyl group is added onto a nucleotide, commonly cytosine. DNA methylation affects many biological processes, including gene ...

DNA methylation is a type of epigenetic mechanism that can have major impacts on regulating gene expression and phenotypic traits, but historically, it has been challenging to study due to the ...