Introduction to Mendelian randomization, the problems with using traditional observational studies to investigate causality, and Randomized controlled trials as the gold standard for causal research.

Basic concepts in quantitative genetics, including Mendelian genetics, gene action (additive, dominant, recessive), heritability, liability threshold model, means, variances, structure of DNA, types ...

IN 1865, an Austrian monk called Gregor Mendel, working to understand hybridisation, uncovered exquisitely simple and reliable patterns of inheritance in varieties of garden pea. In 1900, the patterns ...

A major mouse study found that some inherited traits are passed down through epigenetic changes that break the classic rules of genetics. Researchers discovered hundreds of cases where these chemical ...

For more than a century, heredity has been framed through the tidy logic of Mendel’s pea plants: traits pass from parent to offspring by fixed genetic rules. But a new mouse study suggests that ...