Larger animal models, such as porcine, have been validated as appropriate models of the human disc with respect to biomechanics and biochemistry. They are advantageous for research as the models are ...

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 8, 2025, titled, "Runx1 overexpression induces early onset of intervertebral disc degeneration." In this study, led by ...

Intervertebral disc degeneration, particularly the pathology of the annulus fibrosus, is a critical area of research due to its significant impact on individuals' physical activity and quality of life ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Degenerative disc disease is when one or more of the discs between the vertebrae of the spinal column deteriorate or break down, leading to pain. There may be weakness, numbness, and pain that ...

With chronic back pain, discomfort and uncertainty often outlast solutions. Through a five-year, $3 million National ...

IN 1948 and 1950 Lindblom 1,2 reported his experience with diskography. In these reports he described a method of direct visualization of normal and pathologic lumbar intervertebral disks by means of ...