To get the correct warfarin dose, patients have to have their INR tested. INR—international normalized ratio test—is a common blood test that determines how quickly your blood clots.

Excluding children with target INR above 3. ‡ Results presented as means. § Genotyping for variant alleles *2 and *3 only except in validation dataset, which also included test for *5 ...

However, determining the correct dose of warfarin can be challenging due to its narrow therapeutic window and significant variability in how different individuals respond to the drug. This ...

warfarin dose and vitamin K intake) and genetic factors (CYP2C9 and VKORC1 genotype). In addition, patients with severe CKD had much poorer anticoagulation control (that is, spent less time in the ...

Dosing of Warfarin is delicate as its major adverse effect is hemorrhage or bleeding. This is further complicated by its interaction with many commonly used medications as well as various food ...

Swallow whole; max one tablet per dosing interval ... or other drugs metabolized via CYP2C9. Monitor INR with warfarin. Dyskinesias, hyperkinesia, diarrhea, nausea, abdominal pain, vomiting ...