Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...

All animals possess some capacity for repairing and replacing the lining of their intestines, a process called intestinal regeneration. In mammals, including humans, this constant but relatively minor ...

To better understand our organs and perform tests on a more human-like proxy, researchers are increasingly turning to organoids: miniaturized tissue cultures, usually in the form of organs, that are ...

The human gastrointestinal tract is in a constant state of flux; it hosts a diverse and dynamic community of microbes known as the gut microbiome, and is constantly exposed to things in the ...

A high-fat diet can cause the intestinal lining to weaken, allowing live gut bacteria to travel directly to the brain in mice ...

A cell model that replicates the structure and function of the human intestine has been developed, creating an evaluation platform capable of more accurately predicting adverse effects of new drugs.

Tuft cells are present throughout the intestinal tract as well as in many organs. Studies in mice have shown that when tuft cells sense the presence of pathogens, they signal to immune cells and to ...

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation ...

Researchers found that the hormone oxytocin, known to be involved in regulating feeding and social behavior and until now to be produced mostly in the brain, is also produced in the human intestine.

Organ-Chips as a Platform for Studying Effects of Space on Human Enteric Physiology (Gut on Chip) examines the effect of microgravity and other space-related stress factors on biotechnology company ...

Thanks to lab-grown miniature intestines, researchers at Uppsala University have successfully mapped how aggressive Shigella bacteria infect the human gut. The study opens the door to using cultured ...