Toll-like Receptor 2 Signaling is a Mediator of Apoptosis in Herpes Simplex Virus-infected Microglia
A highly neurotropic HSV-1 17 syn + strain, propagated and purified from rabbit skin fibroblasts, was used for infection studies at a multiplicity of infection (MOI) of 2. After adding virus, culture ...
Herpes simplex viruses (HSV) are ubiquitous, doubleāstranded DNA viruses that establish lifelong infections in human hosts. Central to their cycle is the process of membrane fusion, which permits ...
Approximately two-thirds of the world's population under the age of 50 years have oral or genital herpes simplex type 1 (HSV-1) infection, while one in eight have herpes simplex type 2 (HSV-2) ...
The incidence of neonatal herpes simplex virus (HSV) infections in the UK and Ireland increased dramatically over 15 years, and outcomes remained poor, with mortality and long-term neurologic ...
A photomicrograph image of herpes virus antibodies detected using immunofluorescent staining technique, 1977. Image courtesy CDC/Dr. Craig Lyerla. (Photo by Smith Collection/Gado/Getty Images) A ...
A phase 3 trial finds pritelivir significantly improves cure rates for immunocompromised individuals with refractory HSV infections.
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