Computer generated 3D model, showing a cross-section of the green RNP spirals, blue hemagglutinin, red neuraminidase, and purple m2 ion channels that constitute the structure of the Influenza A Virus ...
In a recent article published in Immunity, researchers proposed that vaccines targeting the immunosubdominant yet conserved hemagglutinin (HA) stem could trigger broadly neutralizing antibodies (bnAbs ...
Influenza pandemics occur at unpredictable intervals when a novel influenza virus arises which can place a major strain on the global healthcare system. These pandemic viruses can cause high levels of ...
Unlike living organisms, to avoid extinction, viruses need to hijack living host machineries to generate new viruses. The devastating respiratory virus, influenza A virus, utilize its hemagglutinin ...
One of the challenges faced when developing influenza virus vaccines is the problem of how to protect populations in the face of spreading pandemics. With the advent of air travel, this readily ...
Review the side-effects of Influenza Vaccine, Recombinant Hemagglutinin as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking ...
In a recent study published in Emerging Infectious Diseases, researchers performed a quantitative assessment of the age-stratified seroprevalence of hemagglutination inhibition (HAI) antibodies ...
Scientists have linked increased resistance of hemagglutinin protein to acidic pH with emergence of the 2009 H1N1 pandemic flu virus; the finding may help spot future pandemic viruses. St. Jude ...
Vaccines work by exposing our immune system to viral proteins. Our immune system then recognizes these proteins as foreign molecules —antigens— and springs into action, neutralizing the threat. As ...
Rupert J. Russell, Philip S. Kerry, David J. Stevens, David A. Steinhauer, Stephen R. Martin, Steven J. Gamblin, John J. Skehel Proceedings of the National Academy of ...
The human immune system protects the body from repeat attacks of the same pathogen by remembering past infections. However, viral antigenic evolution reduces the effectiveness of this immune memory ...
Cold hemagglutinin disease is a chronic hemolytic anemia that is refractory to the usual treatments for hemolytic anemia mediated by a warm-reactive antibody; it may be associated with a low-grade ...
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