Strategic Innovation in Antibody Engineering: Creative Biolabs Addresses Key Challenges in ADCC and Fc Functionality

Creative Biolabs, a global leader in antibody engineering, today announced its optimization of ADCC and Fc-mediated ...
EurekAlert!

"Molecular meridians" reveal how glycans control antibody behavior — unlocking new possibilities for therapeutic antibody design

(A) Structural propagation pathways originating from galactose residues within the Fc-linked glycan. (B) Galactose residues (indicated by yellow circles) suppress glycan mobility by acting as ...
BioWorld

AGEN-1721, a first-in-class Fc-enhanced bifunctional antibody designed to remodel the tumor microenvironment

AGEN-1721 was designed as an Fc-enhanced bifunctional antibody to selectively target FAP and neutralize TGF-β via an optimized TGF-βR2 TRAP moiety fused to an engineered Fc region, with the aim of ...
News Medical

Bridging theory and practice in fragment crystallizable engineering

This article and associated images are based on a poster originally authored by Nikita Kathuria, Annabelle Herrington-Symes, Elisha Moran, Han Yin, Kathryn Armour, Michael Marshall, Nathan Robertson ...