Flash column chromatography was developed in 1978 as an alternative method to long column chromatography. The method aims to isolate a component from a mixture and thereby purify it. It was built from ...

Because GLP-1 analogs carry long carbon chains that add hydrophobicity to the peptide backbone, getting this ratio right is ...

Users often feel a sense of accomplishment when achieving well-defined, isolated spots with a thin-layer chromatography (TLC) plate. Users set up a flash chromatography method, prepare the column, ...

A new method allows chemists to measure how fast a small molecule binds to and unbinds from a protein without modifying or labeling either molecule (Anal. Chem. 2014, DOI: 10.1021/ac503391c).

Researchers have developed a two-step machine-learning method that predicts small-molecule retention times in liquid ...

In Part 2 of "Conversations with Michael Dong," the LCGC column editor discusses HPLC columns for pharmaceutical analysis and ...

Downstream bioprocessing steps have long been a challenge to drug manufacturers, particularly the chromatography step for purification of monoclonal antibodies (mAbs). The complexity of traditional ...

Flash column chromatography is a method of chemical separation that is used to purify chemical mixtures. It is also known as flash purification, due to its function as a purification method. It is ...