The CRISPR/Cas9 gene editing system has revolutionized biomedical research, and has now even been used in the clinic is some rare instances. CRISPR originated in bacteria as a kind of immune defense ...

Researchers have discovered a handful of new CRISPR-Cas systems that could add to the capabilities of the already transformational gene editing and DNA manipulation toolbox. Of the new recruits, one ...

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have harnessed a natural bacterial system to develop a new protein delivery approach that ...

When scientists discovered how bacteria protect themselves against viral invaders, called phages, in the early 2000s, little did they know they'd stumbled upon a revolutionary tool researchers could ...

Joseph “Joe” Kreitz wants to find ways to make sure that molecular tools go to the right tissues and cell types. And now, the MIT graduate student and his colleagues in Feng Zhang’s lab at the Broad ...

A genome-editing technique known as prime editing holds potential for treating many diseases by transforming faulty genes into functional ones. However, the process carries a small chance of inserting ...

Researchers have developed a novel method for controlling the precise amount of protein produced by mammalian cells. A recent research effort from the Massachusetts Institute of Technology (MIT; MA, ...

The baculovirus expression vector system (BEVS) provides a versatile platform for the expression of individual recombinant proteins as well as multimeric protein complexes, virus-like particles, ...

CRISPR-Cas9 gene editing holds immense potential in the field of precision medicine for liver diseases. This innovative technology permits researchers to precisely modify genes linked to liver ...

A detailed look at the predicted structure of a new CRISPR-Cas tool that promises to expand the genomic editing and manipulating abilities of the original. Researchers at Duke University and North ...