Multidimensional chromatography has emerged as a viable alternative to gel-based separation protocols in high-throughput bottom-up proteomics in recent years. Although originally dominated by the ...

Emerging mass spectrometry technologies integrating ion mobility, TIMS–PASEF, and real-time search are enhancing sensitivity, ...

This article takes a deep dive into the history of proteomics from the conception of the term “proteome” up to modern-day advances in bioinformatics and single-cell protein analysis.

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Following on from his exposé of the dearth of specificity in our vocabulary surrounding the proteome and his emphasis that individual proteoforms should be the focus of our proteomic investigations, ...

The Proteomics Core Laboratory is a newly established facility within the Core Research Facilities (CRF) at UMass Lowell. This lab is centered around the Thermo Scientific Orbitrap Astral Mass ...

The practice of bottom-up proteomics relies to a large extent on the separation performance that can be achieved with state-of-the-art nano LC-MS/MS equipment. Depending on the sample complexity or ...

Thought LeadersJohn Yates Professor in the Department of Molecular MedicineScripps Research Institute In this interview conducted at Pittcon 2024, we spoke to Professor John Yates from the Scripps ...

This proteomics-driven approach to drug discovery improves target validation and uncovers insights into undruggable proteins, ...

Proteomics is the large-scale study of proteins, particularly their structures and functions. It involves the systematic identification, quantification, and analysis of the entire protein complement ...