Bile acid metabolism disorders encompass a range of rare, yet clinically significant, genetic conditions that disrupt the normal synthesis and regulation of bile acids by the liver. These conditions, ...

The gallbladder acts as a storage sac for bile, a digestive fluid made by the liver. When a person eats, especially fatty ...

The study details the connection between SCARB2 deficiency and gastrointestinal dysfunction, revealing that the loss of SCARB2 leads to alterations in bile acid metabolism and dysbiosis in the gut ...

A long-standing mystery in bile acid biology has been solved. Bile acids are often introduced as digestion helpers, but they are also powerful chemical messengers that help coordinate metabolism ...

Cholecystectomy is associated with increased sleep energy expenditure, higher lipid oxidation, and a lower respiratory exchange ratio in Indigenous American adults.

The integrated analysis of serum and fecal metabolites uncovers the significant disruption of bile acid metabolites as a key contributing factor in the pathogenesis of DILI. Our study offers promising ...

Persistent itching, yellowing eyes, spider angiomas, or frequent bruising can indicate liver dysfunction. Early diagnosis improves outcomes.