Too much of this enzyme, matrix metalloproteinase 2 (MMP2), might be causing the disturbance to the basement membrane. An ...

In normal liver, hepatic stellate cells (HSCs) are nonparenchymal, quiescent cells whose main functions is to store vitamin A and probably to maintain the normal basement membrane-type matrix.

and essential in cutting through basement membrane barriers 4. The research on urokinase shows that EGCG directly impairs a molecular mechanism active in degradation of extracellular matrix.