Use of a gonadotropin-releasing hormone antagonist is associated with lower risks for death than GnRH agonists, a systematic review and meta-analysis found. Use of degarelix, a gonadotropin-releasing ...
Credit: Getty Images. Real-world data conflict with a recent meta-analysis including patients from highly selected clinical trial populations. Although a recent meta-analysis suggested that ...
Estrogen agonists/antagonists are compounds with tissue-selective actions. The pharmacological goal of these compounds is to produce beneficial estrogenic actions in certain tissues (e.g., bone and ...
Meta-analysis of the impact of single agent daily prednisone on outcomes and toxicities in metastatic castration-resistant prostate cancer (mCRPC). This is an ASCO Meeting Abstract from the 2015 ASCO ...
Focusing on available agents in prostate cancer, experts consider how androgen deprivation therapy impacts risk of cardiovascular disease. John L. Fox, MD, MHA: As far back as 2010, several societies ...
Phase II study of i.v. vinflunine as second line in patients with metastatic breast cancer after anthracycline-taxane failure ...
Shionogi & Co. Ltd. has synthesized spiroheterocycle derivatives acting as 5-HT2A and 5-HT2C receptor antagonists and/or inverse agonists reported to be useful for the treatment of neurodegeneration.
At the ongoing AAAAI meeting in San Antonio, researchers from Escient Pharmaceuticals Inc. presented preclinical data for the Mas-related G-protein coupled receptor X2 (MRGPRX2) antagonist EP-262, ...
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